Glycogen synthase kinase 3 activity during development of bone marrow-derived dendritic cells (DCs) essential for the DC function to induce T helper 2 polarization

Dendritic cells (DCs) polarize naive CD4(+) T cells to either T helper 1 (Th1) or Th2 cells. We examined the role of glycogen synthase kinase 3 (GSK3) activity during DC development from murine bone marrow (BM) cells. DCs were generated by culturing lineage-marker-negative BM cells with granulocyte–...

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Autors principals: Ono, Takenori, Yanagawa, Yoshiki, Iwabuchi, Kazuya, Nonomura, Katsuya, Onoé, Kazunori
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2007
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266003/
https://ncbi.nlm.nih.gov/pubmed/17490435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02627.x
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