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Dendritic cell differentiation with prostaglandin E(2) results in selective attenuation of the extracellular signal-related kinase pathway and decreased interleukin-23 production

The balance between interleukin (IL)-12 and IL-23 production by dendritic cells (DCs) is crucial for the induction of appropriate immune responses. In the present study, we examined the effect of prostaglandin E(2) (PGE(2)) treatment of DCs during differentiation on IL-12 and IL-23 production in res...

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Библиографические подробности
Главные авторы: Hayashi, Fumie, Yanagawa, Yoshiki, Onoé, Kazunori, Iwabuchi, Kazuya
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966759/
https://ncbi.nlm.nih.gov/pubmed/20408896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03275.x
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