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Targeting Cyclic Nucleotide Phosphodiesterase in the Heart: Therapeutic Implications
The second messengers, cAMP and cGMP, regulate a number of physiological processes in the myocardium, from acute contraction/relaxation to chronic gene expression and cardiac structural remodeling. Emerging evidence suggests that multiple spatiotemporally distinct pools of cyclic nucleotides can dis...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966469/ https://ncbi.nlm.nih.gov/pubmed/20632220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-010-9203-9 |
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