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Cysteine-scanning Analysis of Helices TM8, TM9a, and TM9b and Intervening Loops in the YgfO Xanthine Permease: A CARBOXYL GROUP IS ESSENTIAL AT ASP-276

Bacterial and fungal members of the ubiquitous nucleobase-ascorbate transporter (NAT/NCS2) family use the NAT signature motif, a conserved 11-amino acid sequence between amphipathic helices TM9a and TM9b, to define function and selectivity of the purine binding site. To examine the role of flanking...

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Detaylı Bibliyografya
Asıl Yazarlar: Mermelekas, George, Georgopoulou, Ekaterini, Kallis, Alexander, Botou, Maria, Vlantos, Vassilios, Frillingos, Stathis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966115/
https://ncbi.nlm.nih.gov/pubmed/20802252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170415
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