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Purine Substrate Recognition by the Nucleobase-Ascorbate Transporter Signature Motif in the YgfO Xanthine Permease: ASN-325 BINDS AND ALA-323 SENSES SUBSTRATE

The nucleobase-ascorbate transporter (NAT) signature motif is a conserved 11-amino acid sequence of the ubiquitous NAT/NCS2 family, essential for function and selectivity of both a bacterial (YgfO) and a fungal (UapA) purine-transporting homolog. We examined the role of NAT motif in more detail, usi...

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Bibliografski detalji
Glavni autori: Georgopoulou, Ekaterini, Mermelekas, George, Karena, Ekaterini, Frillingos, Stathis
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885222/
https://ncbi.nlm.nih.gov/pubmed/20406814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.120543
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