Conformational Dynamics of the Bovine Mitochondrial ADP/ATP Carrier Isoform 1 Revealed by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

The mitochondrial adenine nucleotide carrier (Ancp) catalyzes the transport of ADP and ATP across the mitochondrial inner membrane, thus playing an essential role in cellular energy metabolism. During the transport mechanism the carrier switches between two different conformations that can be blocke...

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Hlavní autoři: Rey, Martial, Man, Petr, Clémençon, Benjamin, Trézéguet, Véronique, Brandolin, Gérard, Forest, Eric, Pelosi, Ludovic
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966112/
https://ncbi.nlm.nih.gov/pubmed/20805227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146209
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