Structural and Functional Implications of the Instability of the ADP/ATP Transporter Purified from Mitochondria as Revealed by FTIR Spectroscopy

The ADP/ATP transporter shows a high instability when solubilized, making it difficult to obtain functional protein with sufficient purity for long-term spectroscopic studies. When solubilized in the detergent dodecyl maltoside the protein is in equilibrium between the so-called CATR and BA conforma...

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Main Authors: Lórenz-Fonfría, Víctor A., Villaverde, Joaquim, Trézéguet, Véronique, Lauquin, Guy J.-M., Brandolin, Gérard, Padrós, Esteve
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Channels, Receptors, and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303082/
https://ncbi.nlm.nih.gov/pubmed/12829481
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