Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice.

Lp(a) lipoprotein purified from human plasma bound with high affinity to isolated bovine LDL receptors on nitrocellulose blots and in a solid-phase assay. Lp(a) also competed with 125I-LDL for binding to human LDL receptors in intact fibroblasts. Binding led to cellular uptake of Lp(a) with subseque...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hofmann, S L, Eaton, D L, Brown, M S, McConathy, W J, Goldstein, J L, Hammer, R E
Format: Artigo
Langue:Inglês
Publié: 1990
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC296603/
https://ncbi.nlm.nih.gov/pubmed/2139667
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires