An Experimental and Computational Investigation of Spontaneous Lasso Formation in Microcin J25

The antimicrobial peptide microcin J25 (MccJ25) is posttranslationally matured from a linear preprotein into its native lasso conformation by two enzymes. One of these enzymes cleaves the preprotein and the second enzyme installs the requisite isopeptide bond to establish the lasso structure. Analys...

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Библиографические подробности
Главные авторы: Ferguson, Andrew L., Zhang, Siyan, Dikiy, Igor, Panagiotopoulos, Athanassios Z., Debenedetti, Pablo G., James Link, A.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2010
Предметы:
Protein
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965945/
https://ncbi.nlm.nih.gov/pubmed/21044604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.073
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