Systematic Structure-Activity Analysis of Microcin J25

Microcin J25 (MccJ25) is a 21-residue plasmid-encoded ribosomally synthesized lariat-protoknot antibacterial peptide that targets bacterial RNA polymerase. MccJ25 consists of an 8-residue cycle followed by a 13-residue tail that loops back and threads through the cycle. We have performed systematic...

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Hauptverfasser: Pavlova, Olga, Mukhopadhyay, Jayanta, Sineva, Elena, Ebright, Richard H., Severinov, Konstantin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533079/
https://ncbi.nlm.nih.gov/pubmed/18632663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803995200
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