An Experimental and Computational Investigation of Spontaneous Lasso Formation in Microcin J25

The antimicrobial peptide microcin J25 (MccJ25) is posttranslationally matured from a linear preprotein into its native lasso conformation by two enzymes. One of these enzymes cleaves the preprotein and the second enzyme installs the requisite isopeptide bond to establish the lasso structure. Analys...

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Autores principales: Ferguson, Andrew L., Zhang, Siyan, Dikiy, Igor, Panagiotopoulos, Athanassios Z., Debenedetti, Pablo G., James Link, A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2010
Materias:
Protein
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965945/
https://ncbi.nlm.nih.gov/pubmed/21044604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.073
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