Prognostic role of EGFR gene copy number and KRAS mutation in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy

BACKGROUND: Epidermal growth factor receptor (EGFR), evaluated by immunohistochemistry, has been shown to have prognostic significance in patients with colorectal cancer. Gene copy number (GCN) of EGFR and KRAS status predict response and outcome in patients treated with anti-EGFR therapy, but their...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bengala, C, Bettelli, S, Bertolini, F, Sartori, G, Fontana, A, Malavasi, N, Depenni, R, Zironi, S, Del Giovane, C, Luppi, G, Conte, P F
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2010
विषय:
Molecular Diagnostics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965865/
https://ncbi.nlm.nih.gov/pubmed/20842128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605853
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