Prognostic role of EGFR gene copy number and KRAS mutation in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy

BACKGROUND: Epidermal growth factor receptor (EGFR), evaluated by immunohistochemistry, has been shown to have prognostic significance in patients with colorectal cancer. Gene copy number (GCN) of EGFR and KRAS status predict response and outcome in patients treated with anti-EGFR therapy, but their...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bengala, C, Bettelli, S, Bertolini, F, Sartori, G, Fontana, A, Malavasi, N, Depenni, R, Zironi, S, Del Giovane, C, Luppi, G, Conte, P F
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965865/
https://ncbi.nlm.nih.gov/pubmed/20842128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605853
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky