Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition

Molecular chaperone heat shock protein 90 (Hsp90) inhibitors are promising targeted cancer therapeutic drugs, with the advantage that they deplete multiple oncogenic client proteins and modulate all the classical hallmarks of cancer. They are now in clinical trial and show potential for activity in...

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Bibliographic Details
Main Authors: Beloueche-Babari, Mounia, Arunan, Vaitha, Jackson, L. Elizabeth, Perusinghe, Nina, Sharp, Swee Y., Workman, Paul, Leach, Martin O.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2010
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965833/
https://ncbi.nlm.nih.gov/pubmed/21037799
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