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Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition

Molecular chaperone heat shock protein 90 (Hsp90) inhibitors are promising targeted cancer therapeutic drugs, with the advantage that they deplete multiple oncogenic client proteins and modulate all the classical hallmarks of cancer. They are now in clinical trial and show potential for activity in...

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Autors principals: Beloueche-Babari, Mounia, Arunan, Vaitha, Jackson, L. Elizabeth, Perusinghe, Nina, Sharp, Swee Y., Workman, Paul, Leach, Martin O.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965833/
https://ncbi.nlm.nih.gov/pubmed/21037799
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