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Green Tea Polyphenols Potentiate the Action of Nerve Growth Factor to Induce Neuritogenesis: Possible Role of Reactive Oxygen Species

Exogenously administered nerve growth factor (NGF) repairs injured axons, but it does not cross the blood-brain barrier. Thus, agents that could potentiate the neuritogenic ability of endogenous NGF would be of great utility in treating neurological injuries. Using the PC12 cell model, here we show...

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Библиографические подробности
Главные авторы: Gundimeda, Usha, McNeill, Thomas H., Schiffman, Jason E., Hinton, David R., Gopalakrishna, Rayudu
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965808/
https://ncbi.nlm.nih.gov/pubmed/20936703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22519
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