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A Direct Redox Regulation of Protein Kinase C Isoenzymes Mediates Oxidant-induced Neuritogenesis in PC12 Cells

In this study, we have used the PC12 cell model to elucidate the mechanisms by which sublethal doses of oxidants induce neuritogenesis. The xanthine/xanthine oxidase (X/XO) system was used for the steady state generation of superoxide, and CoCl(2) was used as a representative transition metal redox...

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Detalhes bibliográficos
Main Authors: Gopalakrishna, Rayudu, Gundimeda, Usha, Schiffman, Jason Eric, McNeill, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386917/
https://ncbi.nlm.nih.gov/pubmed/18375950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801519200
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