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In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI

Preclinical development of therapeutic agents against cancer could greatly benefit from noninvasive markers of tumor killing. Potentially, the intracellular partial pressure of oxygen (pO(2)) can be used as an early marker of anti-tumor efficacy. Here, the feasibility of measuring intracellular pO(2...

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Autors principals: Kadayakkara, Deepak K.K., Janjic, Jelena M., Pusateri, Lisa B., Young, Won-Bin, Ahrens, Eric T.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965778/
https://ncbi.nlm.nih.gov/pubmed/20860007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22506
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