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In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI
Preclinical development of therapeutic agents against cancer could greatly benefit from noninvasive markers of tumor killing. Potentially, the intracellular partial pressure of oxygen (pO(2)) can be used as an early marker of anti-tumor efficacy. Here, the feasibility of measuring intracellular pO(2...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965778/ https://ncbi.nlm.nih.gov/pubmed/20860007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22506 |
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