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In vivo observation of intracellular oximetry in perfluorocarbon-labeled glioma cells and chemotherapeutic response in the CNS using fluorine-19 MRI

Preclinical development of therapeutic agents against cancer could greatly benefit from noninvasive markers of tumor killing. Potentially, the intracellular partial pressure of oxygen (pO(2)) can be used as an early marker of anti-tumor efficacy. Here, the feasibility of measuring intracellular pO(2...

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Détails bibliographiques
Auteurs principaux: Kadayakkara, Deepak K.K., Janjic, Jelena M., Pusateri, Lisa B., Young, Won-Bin, Ahrens, Eric T.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965778/
https://ncbi.nlm.nih.gov/pubmed/20860007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.22506
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