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Novel Semi-synthetic Method for Generating Full Length β-Amyloid Peptides
Bacterial expression of full length β-amyloid (Aβ) is problematic because of toxicity and poor solubility of the expressed protein, and a strong tendency of Met35 to become oxidized in inclusion bodies. We have developed a semi-synthetic method in which Aβ(1-29) is expressed in bacteria as part of a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965776/ https://ncbi.nlm.nih.gov/pubmed/20593467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21391 |
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