Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects

Spinal Muscular Atrophy (SMA) is caused by diminished function of the Survival of Motor Neuron (SMN) protein, but the molecular pathways critical for SMA pathology remain elusive. We have used genetic approaches in invertebrate models to identify conserved SMN loss of function modifier genes. Drosop...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dimitriadi, Maria, Sleigh, James N., Walker, Amy, Chang, Howard C., Sen, Anindya, Kalloo, Geetika, Harris, Jevede, Barsby, Tom, Walsh, Melissa B., Satterlee, John S., Li, Chris, Van Vactor, David, Artavanis-Tsakonas, Spyros, Hart, Anne C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965752/
https://ncbi.nlm.nih.gov/pubmed/21124729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001172
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados