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Nutrient Control of Yeast PKA Activity Involves Opposing Effects on Phosphorylation of the Bcy1 Regulatory Subunit

GPB1 and GPB2 encode kelch repeat-containing proteins that regulate protein kinase A (PKA) in yeast by a cAMP-independent process. Here we show that Gpb1 and Gpb2 stimulate phosphorylation of PKA regulatory subunit Bcy1 in low glucose concentrations, thereby promoting the inhibitory function of Bcy1...

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Sonraí Bibleagrafaíochta
Main Authors: Budhwar, Roli, Lu, Ailan, Hirsch, Jeanne P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965690/
https://ncbi.nlm.nih.gov/pubmed/20826609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-05-0388
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