Rapamycin regulates Stearoyl CoA Desaturase 1 Expression in Breast Cancer

mTOR (mammalian target of rapamycin) signaling is a central regulator of protein translation, cell growth and metabolism. Alterations of the mTOR signaling pathway are common in cancer, making mTOR a promising therapeutic target. In clinical trials, rapamycin analogs have shown modest response rates...

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Hauptverfasser: Luyimbazi, David, Akcakanat, Argun, McAuliffe, Priscilla F., Zhang, Li, Singh, Gopal, Gonzalez-Angulo, Ana Maria, Chen, Huiqin, Do, Kim-Anh, Zheng, Yuhuan, Hung, Mien-Chie, Mills, Gordon B., Meric-Bernstam, Funda
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965451/
https://ncbi.nlm.nih.gov/pubmed/20876744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0980
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