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Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA
Telomerase extends the 3′-ends of linear chromosomes by adding conserved telomeric DNA repeats and is essential for cell proliferation and genomic stability. Telomerases from all organisms contain a telomerase reverse transcriptase and a telomerase RNA (TER), which together provide the minimal funct...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965242/ https://ncbi.nlm.nih.gov/pubmed/20554853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq525 |
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