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YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA

Autosomal dominant dyskeratosis congenita (DKC) has been linked to mutations in the RNA component of telomerase, the ribonucleoprotein responsible for telomere maintenance. Recent studies have investigated the role of the GC (107–108) → AG mutation in the conserved P3 helix in the pseudoknot domain...

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Autores principales: THEIMER, CARLA A., FINGER, L. DAVID, FEIGON, JULI
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2003 by RNA Society 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370499/
https://ncbi.nlm.nih.gov/pubmed/14624001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5152303
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