Regulators of the Proteasome Pathway, Uch37 and Rpn13, Play Distinct Roles in Mouse Development

Rpn13 is a novel mammalian proteasomal receptor that has recently been identified as an amplification target in ovarian cancer. It can interact with ubiquitin and activate the deubiquitinating enzyme Uch37 at the 26S proteasome. Since neither Rpn13 nor Uch37 is an integral proteasomal subunit, we ex...

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Detalhes bibliográficos
Main Authors: Al-Shami, Amin, Jhaver, Kanchan G., Vogel, Peter, Wilkins, Carrie, Humphries, Juliane, Davis, John J., Xu, Nianhua, Potter, David G., Gerhardt, Brenda, Mullinax, Robert, Shirley, Cynthia R., Anderson, Stephen J., Oravecz, Tamas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965108/
https://ncbi.nlm.nih.gov/pubmed/21048919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013654
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