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Tamoxifen-Independent Recombination in the RIP-CreER Mouse

BACKGROUND: The inducible Cre-lox system is a valuable tool to study gene function in a spatial and time restricted fashion in mouse models. This strategy relies on the limited background activity of the modified Cre recombinase (CreER) in the absence of its inducer, the competitive estrogen recepto...

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Bibliografiske detaljer
Main Authors: Liu, Yanmei, Suckale, Jakob, Masjkur, Jimmy, Magro, Maria Grazia, Steffen, Anja, Anastassiadis, Konstantinos, Solimena, Michele
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965077/
https://ncbi.nlm.nih.gov/pubmed/21063464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013533
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