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Tamoxifen-Independent Recombination in the RIP-CreER Mouse

BACKGROUND: The inducible Cre-lox system is a valuable tool to study gene function in a spatial and time restricted fashion in mouse models. This strategy relies on the limited background activity of the modified Cre recombinase (CreER) in the absence of its inducer, the competitive estrogen recepto...

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Autors principals: Liu, Yanmei, Suckale, Jakob, Masjkur, Jimmy, Magro, Maria Grazia, Steffen, Anja, Anastassiadis, Konstantinos, Solimena, Michele
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965077/
https://ncbi.nlm.nih.gov/pubmed/21063464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013533
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