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Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques

Rapid progression to AIDS is a significant problem, especially in developing countries, where the majority of HIV-infected individuals reside. As rapid disease progression is also frequently observed in SIV-infected macaques, they represent a valuable tool to investigate the pathogenesis of this con...

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Bibliografische gegevens
Hoofdauteurs: Titanji, Kehmia, Velu, Vijayakumar, Chennareddi, Lakshmi, Vijay-Kumar, Matam, Gewirtz, Andrew T., Freeman, Gordon J., Amara, Rama R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964982/
https://ncbi.nlm.nih.gov/pubmed/20972331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43271
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