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Frequent Deregulations in the Hedgehog Signaling Network and Cross-Talks with the Epidermal Growth Factor Receptor Pathway Involved in Cancer Progression and Targeted Therapies

The hedgehog (Hh)/glioma-associated oncogene (GLI) signaling network is among the most important and fascinating signal transduction systems that provide critical functions in the regulation of many developmental and physiological processes. The coordinated spatiotemporal interplay of the Hh ligands...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mimeault, Murielle, Batra, Surinder K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964899/
https://ncbi.nlm.nih.gov/pubmed/20716670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.109.002329
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