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Frequent Deregulations in the Hedgehog Signaling Network and Cross-Talks with the Epidermal Growth Factor Receptor Pathway Involved in Cancer Progression and Targeted Therapies

The hedgehog (Hh)/glioma-associated oncogene (GLI) signaling network is among the most important and fascinating signal transduction systems that provide critical functions in the regulation of many developmental and physiological processes. The coordinated spatiotemporal interplay of the Hh ligands...

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Detalhes bibliográficos
Main Authors: Mimeault, Murielle, Batra, Surinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964899/
https://ncbi.nlm.nih.gov/pubmed/20716670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.109.002329
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