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Biochemical and Structural Characterization of Bisubstrate Inhibitors of BasE, the Self-standing Non-Ribosomal Peptide Synthetase Adenylate-Forming Enzyme of Acinetobactin Synthesis,(‡)
The human pathogen Acinetobacter baumannii produces a siderophore called acinetobactin that is derived from one molecule each of threonine, histidine, and 2,3-dihydroxybenzoic acid (DHB). The activity of several non-ribosomal peptide synthetase (NRPS) enzymes is used to combine the building blocks i...
Bewaard in:
Hoofdauteurs: | , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2010
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964879/ https://ncbi.nlm.nih.gov/pubmed/20853905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101226n |
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