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Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes

BACKGROUND: The Poly(ADP-ribose)polymerase (PARP) superfamily was originally identified as enzymes that catalyze the attachment of ADP-ribose subunits to target proteins using NAD(+ )as a substrate. The family is characterized by the catalytic site, termed the PARP signature. While these proteins ca...

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Autors principals: Citarelli, Matteo, Teotia, Sachin, Lamb, Rebecca S
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964712/
https://ncbi.nlm.nih.gov/pubmed/20942953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-308
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