Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication

Interferon alpha (IFN-α) binds to a cell surface receptor that activates the Jak-Stat signaling pathway. A critical component of this pathway is the translocation of interferon stimulated gene factor 3 (a complex of three proteins Stat1, Stat2 and IRF9) to the nucleus to activate antiviral genes. A...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Poat, Bret, Hazari, Sidhartha, Chandra, Partha K, Gunduz, Feyza, Alvarez, Xavier, Balart, Luis A, Garry, Robert F, Dash, Srikanta
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964675/
https://ncbi.nlm.nih.gov/pubmed/20939906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-265
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares