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SUMO Modification Regulates Transcriptional Activity of XBP1
The unfolded protein response (UPR), a cellular defense mechanism against misfolded protein accumulation in the endoplasmic reticulum (ER), is associated with many human diseases such as aging, cancer and diabetes. X-box binding protein 1 (XBP1), a key transcription factor of the UPR, is critical in...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964647/ https://ncbi.nlm.nih.gov/pubmed/20408817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100193 |
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