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Tim3 binding to galectin-9 stimulates antimicrobial immunity
T cell immunoglobulin and mucin domain 3 (Tim3) is a negative regulatory molecule that inhibits effector T(H)1-type responses. Such inhibitory signals prevent unintended tissue inflammation, but can be detrimental if they lead to premature T cell exhaustion. Although the role of Tim3 in autoimmunity...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964580/ https://ncbi.nlm.nih.gov/pubmed/20937702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100687 |
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