Characterization of sphingosine-1-phosphate lyase activity by ESI-LC/MS/MS quantitation of (2E)-hexadecenal

Sphingosine-1-phosphate (S1P) is a sphingolipid signaling molecule crucial for cell survival and proliferation. S1P-mediated signaling is largely controlled through its biosynthesis and degradation, and S1P lyase (S1PL) is the only known enzyme, which irreversibly degrades sphingoid base-1-phosphate...

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Bibliografiske detaljer
Main Authors: Berdyshev, Evgeny V., Goya, Jonathan, Gorshkova, Irina, Prestwich, Glenn D., Byun, Hoe-Sup, Bittman, Robert, Natarajan, Viswanathan
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964418/
https://ncbi.nlm.nih.gov/pubmed/20804717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.08.026
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