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Impact of Pre-Existing Elastic Matrix on TGF-β1 and HA Oligomer-Induced Regenerative Repair by Rat Aortic Smooth Muscle Cells

Regenerating elastic matrices lost to disease (e.g. in aneurysms) is vital to re-establishing vascular homeostasis but is challenged by poor elastogenicity of post-neonatal cells. We previously showed exogenous hyaluronan oligomers (HA-o) and TGF-β1 to synergistically enhance tropo and matrix elasti...

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Autors principals: Gacchina, Carmen E., Ramamurthi, Anand
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964397/
https://ncbi.nlm.nih.gov/pubmed/20653044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.286
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