Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked Mutants

BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized pathologically by the presence in the brain of intracellular protein inclusions highly enriched in aggregated alpha-synuclein (α-Syn). Although it has been established that progression of the disease...

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Main Authors: Roodveldt, Cintia, Labrador-Garrido, Adahir, Gonzalez-Rey, Elena, Fernandez-Montesinos, Rafael, Caro, Marta, Lachaud, Christian C., Waudby, Christopher A., Delgado, Mario, Dobson, Christopher M., Pozo, David
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964342/
https://ncbi.nlm.nih.gov/pubmed/21048992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013481
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