Chaperoned amyloid proteins for immune manipulation: α-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype

α-Synuclein (αSyn) is a 140-residue amyloid-forming protein whose aggregation is linked to Parkinson's disease (PD). It has also been found to play a critical role in the immune imbalance that accompanies disease progression, a characteristic that has prompted the search for an effective αSyn-b...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Labrador-Garrido, Adahir, Cejudo-Guillén, Marta, Klippstein, Rebecca, De Genst, Erwin J, Tomas-Gallardo, Laura, Leal, María M, Villadiego, Javier, Toledo-Aral, Juan J, Dobson, Christopher M, Pozo, David, Roodveldt, Cintia
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386917/
https://ncbi.nlm.nih.gov/pubmed/25866630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.39
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