Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models

To examine the role of breast cancer stem cells (BCSCs) in metastasis, we generated human-in-mouse breast cancer orthotopic models using patient tumor specimens, labeled with optical reporter fusion genes. These models recapitulate human cancer features not captured with previous models, including s...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Liu, Huiping, Patel, Manishkumar R., Prescher, Jennifer A., Patsialou, Antonia, Qian, Dalong, Lin, Jiahui, Wen, Susanna, Chang, Ya-Fang, Bachmann, Michael H., Shimono, Yohei, Dalerba, Piero, Adorno, Maddalena, Lobo, Neethan, Bueno, Janet, Dirbas, Frederick M., Goswami, Sumanta, Somlo, George, Condeelis, John, Contag, Christopher H., Gambhir, Sanjiv Sam, Clarke, Michael F.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2010
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964232/
https://ncbi.nlm.nih.gov/pubmed/20921380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006732107
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