HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology

We present HepatoNet1, the first reconstruction of a comprehensive metabolic network of the human hepatocyte that is shown to accomplish a large canon of known metabolic liver functions. The network comprises 777 metabolites in six intracellular and two extracellular compartments and 2539 reactions,...

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Main Authors: Gille, Christoph, Bölling, Christian, Hoppe, Andreas, Bulik, Sascha, Hoffmann, Sabrina, Hübner, Katrin, Karlstädt, Anja, Ganeshan, Ramanan, König, Matthias, Rother, Kristian, Weidlich, Michael, Behre, Jörn, Holzhütter, Herrmann-Georg
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964118/
https://ncbi.nlm.nih.gov/pubmed/20823849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.62
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