The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

The retromer complex is required for the efficient endosome-to-Golgi retrieval of the CIMPR, sortilin, SORL1, wntless and other physiologically important membrane proteins. Retromer comprises two protein complexes that act together in endosome-to-Golgi retrieval; the cargo-selective complex is a tri...

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Bibliographic Details
Main Authors: Harbour, Michael E., Breusegem, Sophia Y. A., Antrobus, Robin, Freeman, Caroline, Reid, Evan, Seaman, Matthew N. J.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2010
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964111/
https://ncbi.nlm.nih.gov/pubmed/20923837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.071472
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