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RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation
Retromer is a vital element of the endosomal protein sorting machinery and comprises two subcomplexes that operate together to sort membrane proteins (cargo) and tubulate membranes. Tubules are formed by a dimer of sorting nexins, a key component of which is SNX1. Cargo selection is mediated by the...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004978/ https://ncbi.nlm.nih.gov/pubmed/24643499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.144659 |
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