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Analysis of the Retromer complex-WASH complex interaction illuminates new avenues to explore in Parkinson disease
The retromer complex mediates endosomal protein sorting by concentrating membrane proteins (cargo) into nascent tubules formed through the action of sorting nexin (SNX) proteins. The WASH complex is recruited to endosomes by binding to the VPS35 subunit of retromer and facilitates cargo protein sort...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Landes Bioscience
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106150/ https://ncbi.nlm.nih.gov/pubmed/25067992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.29483 |
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