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Cytochrome c oxidase loses catalytic activity and structural integrity during the aging process in Drosophila melanogaster
The hypothesis, that structural deterioration of cytochrome c oxidase (CcO) is a causal factor in the age-related decline in mitochondrial respiratory activity and an increase in H(2)O(2) generation, was tested in Drosophila melanogaster. CcO activity and the levels of seven different nuclear DNA-en...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964050/ https://ncbi.nlm.nih.gov/pubmed/20833144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.09.009 |
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