Stimulation of CD5 enhances signal transduction by the T cell antigen receptor.

After the addition of a CD3 monoclonal antibody to peripheral T cells that have been previously stimulated with phytohemagglutinin, inositol phosphates are produced at a rapid rate for 2 min and at a much slower rate thereafter. Stimulation of CD5 allows CD3-mediated production of inositol phosphate...

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Main Authors: Imboden, J B, June, C H, McCutcheon, M A, Ledbetter, J A
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC296396/
https://ncbi.nlm.nih.gov/pubmed/1688565
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