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Stimulation of CD5 enhances signal transduction by the T cell antigen receptor.

After the addition of a CD3 monoclonal antibody to peripheral T cells that have been previously stimulated with phytohemagglutinin, inositol phosphates are produced at a rapid rate for 2 min and at a much slower rate thereafter. Stimulation of CD5 allows CD3-mediated production of inositol phosphate...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Imboden, J B, June, C H, McCutcheon, M A, Ledbetter, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296396/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1688565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114402
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