Influence of Hsp90 and HDAC Inhibition and Tubulin Acetylation on Perinuclear Protein Aggregation in Human Retinal Pigment Epithelial Cells

Retinal pigment epithelial (RPE) cells are continually exposed to oxidative stress that contributes to protein misfolding, aggregation and functional abnormalities during aging. The protein aggregates formed at the cell periphery are delivered along the microtubulus network by dynein-dependent retro...

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Detalhes bibliográficos
Main Authors: Ryhänen, Tuomas, Viiri, Johanna, Hyttinen, Juha M. T., Uusitalo, Hannu, Salminen, Antero, Kaarniranta, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963810/
https://ncbi.nlm.nih.gov/pubmed/20981255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/798052
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